Neurodegenerative Diseases

Neurodegenerative disease is a significant challenge to patients and their loved ones. These conditions, such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), involve the progressive loss of neurons in the brain or spinal cord, leading to debilitating symptoms and a decline in quality of life. ⁽¹⁾

In recent years, there has been growing interest in the potential of stem cell therapy for the treatment of neurodegenerative diseases. Stem cells are unique cells that have the remarkable ability to differentiate into various cell types in the body. This regenerative medicine approach holds promise in addressing the underlying causes of these diseases and potentially restoring lost function.

At Daisy Stem Cell Therapy, under the guidance of Dr. John C. Haasis III, we understand the complexities of neurodegenerative diseases and the impact they have on individuals and their families. We offer comprehensive evaluations to determine if stem cell therapy is a viable option for you. Our dedicated team will provide personalized care and support throughout your treatment journey.

To explore the potential of stem cell therapy for neurodegenerative diseases in Spartanburg, Greenville, Columbia, Anderson, or Asheville, schedule an appointment with Dr. Haasis at our Greenville practice. You can reach us at (864) 775-5682 or send us a message to learn more about our services. Let us help you regain hope and improve your quality of life.

Neurodegenerative Diseases

Parkinson’s Disease

Parkinson’s disease is a neurodegenerative disorder that affects 1 to 2 in every 1000 people at any given time. ⁽²⁾ It affects the central nervous system, specifically, the part of the brain called the substantia nigra. This condition is characterized by a progressive loss of dopamine-producing cells in the brain, leading to a deficiency of dopamine, a crucial neurotransmitter involved in regulating movement.

As a movement disorder, Parkinson’s disease manifests in various ways. The most common symptoms include tremors, which are involuntary shaking movements, often starting in the hands or fingers. Rigidity, another hallmark of Parkinson’s, refers to muscle stiffness and resistance to movement, making it difficult for patients to perform daily tasks. Bradykinesia, or slowness of movement, is also commonly observed, as well as postural instability, which can lead to balance problems and an increased risk of falls.

Alzheimer’s Disease

Alzheimer’s disease is a neurodegenerative disorder characterized by progressive memory loss, cognitive decline, and impairment in daily functioning. It affects roughly 6.2 million people over 65 in the United States alone. ⁽³⁾ 

The brain cells of individuals with Alzheimer’s disease undergo significant changes, leading to the formation of abnormal structures known as plaques and tangles. These plaques are made up of a sticky protein called amyloid beta, which accumulates between the brain cells, disrupting their communication and function. Tangles, on the other hand, consist of twisted strands of a protein called tau, which form within the brain cells, further impairing their ability to transmit information effectively.

Huntington’s Disease

Huntington’s disease is a neurodegenerative disorder caused by a genetic mutation. This condition is characterized by a combination of involuntary movements, cognitive decline, and psychiatric symptoms. The condition is hereditary, meaning it can be passed down from one generation to another. The onset of Huntington’s disease usually occurs in adulthood, typically between the ages of 30 and 50. As the disease progresses, individuals may experience a wide range of symptoms that can significantly impact their quality of life.

One of the primary features of Huntington’s disease is the presence of abnormal movements, known as chorea. These movements are involuntary and can manifest as jerking or writhing motions. Over time, these movements may become more severe and affect a person’s ability to perform everyday tasks.

ALS

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a neurodegenerative disorder that affects the motor neurons in the brain and spinal cord. This progressive condition leads to muscle weakness, muscle atrophy, and ultimately, the loss of voluntary muscle control.

The exact cause of ALS is still unknown, but it is believed to be a combination of genetic and environmental factors. The disease typically starts with muscle weakness or stiffness, often in the arms or legs, and gradually spreads to other parts of the body. As ALS progresses, individuals may experience difficulty speaking, swallowing, and breathing.

MS

Multiple sclerosis (MS) is a chronic disease that affects the central nervous system, specifically the brain and spinal cord. It is an autoimmune disorder, which means that the immune system mistakenly attacks the body’s own tissues. In the case of MS, the immune system targets the protective covering of nerve fibers called myelin.

Common symptoms of multiple sclerosis include fatigue, difficulty walking, numbness or tingling in the limbs, muscle weakness, problems with coordination and balance, blurred vision, and cognitive impairment. These symptoms can greatly impact a person’s quality of life and daily functioning.

Other Neurodegenerative Diseases

What Causes Neurodegenerative Disease?

It is important to note that the exact causes of many neurodegenerative diseases are still not fully understood. However, research suggests a combination of genetic, environmental, and lifestyle factors play a role in their development. Genetic mutations, exposure to toxins, oxidative stress, inflammation, and impaired protein processing are among the potential factors that can contribute to the onset and progression of these diseases.

Common signs of neurodegenerative disease include:

What Are MSCs?

One type of stem cell that has shown promise in the treatment of neurodegenerative disease is mesenchymal stem cells (MSCs). These cells can be isolated from various sources, such as bone marrow or adipose tissue. MSCs possess anti-inflammatory properties and the ability to stimulate tissue repair and regeneration. ⁽⁴⁾ When introduced into the body, they can migrate to the site of injury or degeneration and promote healing through their paracrine effects and immunomodulatory capabilities.

Stem cell therapy involves the administration of MSCs either directly into the affected area or through intravenous infusion. The goal is to provide a supportive environment for the remaining neurons, promote the growth of new neurons, and modulate the immune response to reduce inflammation.

While the field of stem cell therapy for neurodegenerative diseases is still evolving, early research and clinical trials have shown promising results. Patients have reported improvements in motor function, cognition, and overall quality of life. However, it is important to note that more extensive research is needed to establish the safety and efficacy of this treatment approach.

Personal Consultation

During your personal consultation, Dr. Haasis will thoroughly evaluate your condition by examining the type of neurodegenerative disease you are dealing with. Understanding the specific characteristics of your condition, such as the extent of neuronal damage or the affected areas of the brain, is essential for determining the potential efficacy of stem cell therapy. By assessing your medical history and discussing your symptoms, Dr. Haasis can develop a comprehensive understanding of your individual needs.

A Multidimensional Approach

Neurodegenerative diseases are complex conditions that require a multidimensional approach to treatment. While stem cell therapy is not a cure, it has shown promise in managing symptoms and slowing down disease progression in some cases. Dr. Haasis will provide you with a detailed explanation of how stem cell therapy fits into the overall management of your neurodegenerative disease. This comprehensive approach to treatment involves collaborating with other healthcare professionals to ensure optimal care and disease management.

Stem Cell Therapy in the Carolinas

If you or a loved one is seeking alternative treatment options for neurodegenerative diseases, we encourage you to reach out to us at Daisy Stem Cell Therapy. Our team of experienced professionals will provide you with comprehensive information, and personalized guidance, and determine if you are a suitable candidate for stem cell therapy. Together, we can explore the possibilities of regenerative medicine and strive towards a future with improved outcomes for those affected by neurodegenerative diseases.

Cost of Stem Cell Therapy in Spartanburg

Medical costs associated with stem cell therapy can vary depending on a patient’s treatment plan. For more information about our services in Spartanburg, Greenville, Columbia, Anderson, or Asheville, and to speak with Dr. Haasis in person, please contact (864) 775-5682 or submit an inquiry using this simple form on our website.

References

1. Sivandzade F, Cucullo L. Regenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview. International Journal of Molecular Sciences. 2021;22(4):2153. doi:https://doi.org/10.3390/ijms22042153 
2. Zafar S, Yaddanapudi SS. Parkinson Disease. PubMed. Published 2020. https://www.ncbi.nlm.nih.gov/books/NBK470193/#:~:text=PD%20affects%201%20to%202 
3. Alzheimer’s Association. 2021 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia. 2021;17(3). doi:https://doi.org/10.1002/alz.12328 
4. Li X, Wei Z, Zhang W, et al. Anti-Inflammatory Effects of Magnetically Targeted Mesenchymal Stem Cells on Laser-Induced Skin Injuries in Rats. International Journal of Nanomedicine. 2020;15:5645-5659. doi:https://doi.org/10.2147/IJN.S258017